Phytochemical analysis, investigation of antioxidant and anti-inflammatory activities of ethanolic and aqueous extracts of roots of Combretum glutinosum Perr. ex DC from Cote d'Ivoire

The phytochemical, antioxidant, and anti-inflammatory potential of root (ethanol aqueous) extracts Combretum glutinosum was investigated in this study. Their antioxidant activity determined using an vitro DPPH radical scavenging assay. ethanol extract had the lowest IC50 (0.055 mg/mL), which is comparable to vitamin C. Phytochemical screening revealed presence sterols polyterpenes, polyphenols, alkaloids, flavonoids, catechin tannins, gallic saponosides, terpenoids, mucilages, anthocyanins, volatile oils, cardiac glycosides. significantly inhibit development paw edema induced by carrageenan. Anti-inflammatory studies showed that inflammation inhibition 200 mg/kg body weight all lower than standard diclofenac (20 mg/kg) first hours. At third hour, ethanolic aqueous higher standard. This study have effects can act as effective antioxidant.